Premature Centromere Division: A cytogenetic study.
نویسندگان
چکیده
منابع مشابه
Variegated aneuploidy related to premature centromere division (PCD) is expressed in vivo and is a cancer-prone disease.
We present three patients with variegated aneuploidy and premature centromere division (PCD), a rare chromosomal abnormality in humans. Comparison of these three and eight other patients with variegated aneuploidy related to PCD demonstrates a phenotype comprising most frequently microcephaly, CNS anomalies (with cerebellar affection and migration defects), mental retardation, pre-and postnatal...
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An increased frequency of mitoses with centromere separation affecting all chromosomes was found in lymphocyte cultures of couples with recurrent spontaneous abortions. This anomaly was recorded in six individuals out of seventy couples (one hundred and forty individuals) with recurrent miscarriages. The abnormal behaviour of centromeres may predispose the individual to cell division errors, th...
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The importance of chromosomal abnormalities in etiology of premature ovarian failure (POF) is well known but in many cases, POF still remains idiopathic. We investigated the frequency and type of chromosomal aberrations in Iranian women diagnosed with idiopathic POF. Standard cytogenetic analysis was carried out in a total of 179 patients. Karyotype analysis of these patients revealed that 161 ...
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متن کاملCytogenetic study of two Alhagi species
Background & Aim: Alhagi genus has two important medicinal plant species in Iran, including Alhagi pseudoalhagi, and A. graecorum (known “Kharshotor” in Persian). These plants are distributed in Iran like weeds. Generally, Alhagi is used as an anti-hemorrhoid, laxative and diuretic. Manna in both species produced by activity of a kind of insect on <...
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ژورنال
عنوان ژورنال: CYTOLOGIA
سال: 1995
ISSN: 0011-4545,1348-7019
DOI: 10.1508/cytologia.60.159